Once hits are identified, medicinal chemists modify these compounds to optimize their properties
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Drugs need to be stable in the body to have a longer half-life and maintain efficacy over time
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This refers to the extent and rate at which the active ingredient or drug is absorbed into the bloodstream after oral administration.
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Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Later chemical libraries of synthetic small molecules.
Despite advances in technology and understanding of biological systems, drug discovery is still a lengthy, expensive.
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